The main purpose of this work is to understand the relationship between structural processes of urban development, associated with the fragmented reconfiguration of the city, with particular dynamics of social integration and social cohesion, through the analysis of sociability of the people in the city. The main hypothesis of this study is that urban space acts as a structuring structure of social relations and sociability patterns of residents in those spaces. This relationship is unequal, thereby affecting the opportunities for social interaction and, in consequence, affecting possibilities of integration and social cohesion in the city. Specifically, the proposed hypothesis is a strong local integration and metropolitan isolation of residents in vulnerable areas of the city, which accumulate many social and territorial disadvantages. Meanwhile, it is expected a smaller local integration, with greater connections to metropolitan scale, by the residents of middle and upper middle class. The methodology corresponds to an integrated strategy including social network analysis and exploratory statistics. Sociability networks of individuals living in the neighborhoods of El Barrero (Huechuraba) and Villa Macul (Macul), located in different sectors of Metropolitan Area of Santiago are analyzed.